World Health Organization reports that 15% of adolescents (aged 10-19 years) experience mental disorders (2024). To address this global challenge, this paper explores how we design culturally sensitive and meaningful technology to empower high school teenagers and support their holistic development by applying the Low-Dissipation Optimization State (LDoS) framework and its core technique, mind-holding (Lun et al., 2022).

Collaborating with a local High School in Guangzhou, we developed a "Mind-Holding Pod (Mind-Body Wellness Pod)" to provide students with a space for relaxation and focus enhancement, rooted from China’s traditional culture. Guided by “The Yellow Emperor’s Inner Canon” on the unity of body and mind, the Pod integrates advanced brain-computer interface (BCI) technology and neuroscience to help students achieve mind-holding mindfulness through environmental design and experiential activities. Chinese traditional philosophy of Five Elements (Wood, Fire, Earth, Metal, Water) is used to emphasize embodiment and situatedness, and Five Tones (Gong, Shang, Jue, Zhi, Yu) is used as music therapy to enhance the Pod experience.

In a discussion how novel interaction techniques and fair algorithms are integrated in this indigenous community-engaged design endeavor (Sun, in press), we will compare the two mindful design models between the West and the East. While the Western model promotes an individualist approach of mindfulness that reduce the sufferings of stress, anxiety, anger, and depression into individual ailment and weakness (Nixon, 2020), Traditional Chinese Medicine highlights the Unity of Heaven and Humanity (天人合一). This holistic approach applied in this design case, i.e., the Low-Dissipation Optimization State (LDoS) framework and the mind-holding technique, aims to engage adolescent users with embodied activities, mediated by artifacts that is situated from the Chinese traditional culture such as herbal incense and tea ceremonies, to help students be socially connective and bridge differences. 

Introduction: Since the implantation of Flexner report in 1910, it was instituted that the medication of choice considered scientific were the ones produced by the pharmaceutical industry. According to Hippocrates, the father of medicine, we need to use older ancient medical traditions prior to the knowledge we have nowadays. So, if we analyze from the point of view of Traditional Chinese Medicine, cancer comes from energy deficiency and formation of internal Fire. In research analyzing the energy of all my patients in Brazil from 2015 to 2020, before the COVID-19 pandemic, I demonstrated that 90% of all of them, were in the lowest level of energy, in the five internal massive organs of the Five Elements theory of Traditional Chinese Medicine. These organs are Liver, Heart, Spleen, Lungs and Kidney. Each organ is responsible for the production of one internal energy for our health, for our survival and our immune system among many other functions. If we analyze these patients nowadays (in 2025), we can see that 100% of the population globally are in this situation. This is caused by the modernization of telecommunication after the implementation of 4G and 5G technology, leading to a state of a GLOBAL IMMUNODEFICIENCY. Cancer nowadays is also caused by this lack of energy inside these five internal massive organs, due to the fact that our energy is responsible for control the abnormal growth of malignant cells inside the body and when this condition is disrupted, the malignant cells can growth without control leading to cancer formation. The prompt treatment replenishing the energy of these five internal massive organs using highly diluted medications according to the theory of Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine created by myself in 2015 , can increase again the energy of our body and can increase our immune system, leading to control the abnormal growth of malignant cells inside the body, curing the patients suffering from this disease. To show how quick we can cure this disease, I will show four cases reports of patients suffering from cancer (2 women with breast cancer and 2 men with prostate cancer). The first was a 46 years-old female patient that had a right breast cancer of about 9 cm in diameter and between the time to do the surgery, I measured the energy of her five internal massive organs and all of them were in the lowest level of energy, rated one out of eight. She began to treat this condition using acupuncture, and replenishing the energy of these organs and in one week, this tumor reduced to 3cm, without using chemotherapy or radiotherapy or surgery. The second patient was a 36 years-old female patient with a breast cancer of 5 cm and using these highly diluted medications according to the theory of Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine and acupuncture, she reduced this tumor to 1cm in 4 hours of ingestion of these medications. After one day, this tumor disappeared completely. The third case report was a 60 years-old male patient with prostate cancer. Before he went to robotic surgery, his PSA was 20ng/dl. After this surgery, it increased to 40 ng/dl. After begin to use these highly diluted medications to increase the energy of the five internal massive organs, to increase his immune system, the PSA reduced to 0,2 ng/dl in the first month of treatment and to 0.02ng/dl in the second month of treatment. The fourth case report is a 76 years-old male patient with prostate cancer with initial PSA of 10,3ng/dl. After two months of treatment, using highly diluted medications according to Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine, Chinese dietary counseling and acupuncture, his PSA reduced to 5 ng/dl after two months of treatment. The conclusion of this study is to show that cancer has a cure and we need to treat the cause nowadays, that it is to increase the energy of the five internal massive organs of the Five Elements theory of traditional Chinese Medicine using highly diluted medications according to the theory of Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine created by myself. The use of any highly concentrated medications used in the conventional treatment can reduce even more these energies and lead to complication or death of these patients suffering from this disease. 

Ferromagnetic nanosystems represent a transformative frontier in biomedicine, leveraging their unique magnetic properties for diverse therapeutic and diagnostic applications. This paper explores two groundbreaking phenomena—magnetic hyperthermia and magnetically activated adenosine triphosphate (ATP) reactions—to elucidate the role of iron and manganese oxide nanosystems in enhancing electrodynamical and biothermophysical processes.

In magnetic hyperthermia, ferromagnetic nanoparticles (e.g., Fe₃O₄, MnO₂) are engineered to generate localized heat under alternating magnetic fields (AMF), enabling targeted cancer cell destruction while minimizing damage to healthy tissues. Key challenges, such as optimizing the specific absorption rate (SAR) and mitigating eddy current effects, are discussed alongside advances in self-regulating nanomaterials with controlled Curie temperatures (e.g., Ni/C and La₁₋ₓAgₓMnO₃ nanocomposites).

Parallelly, the paper investigates ATP activation via magnetic impurities (Fe²⁺, Mn²⁺), employing vibrational spectroscopy (Raman/IR) to probe how these ions modulate ATP hydrolysis kinetics and energy transfer mechanisms. The interplay between magnetic nanoparticles and ATPase-driven phosphorylation reactions is analyzed, offering insights into cellular energy manipulation and potential therapeutic applications.

By bridging material science, biophysics, and clinical innovation, this work underscores the potential of ferromagnetic nanosystems to revolutionize oncology and bioenergetics, while highlighting future directions for low-toxicity, high-efficiency nanotherapies.

This paper addresses the role of lithium both in its geological origins and in its therapeutic use in psychiatry, highlighting the implications of its extraction and medical application. Under standard conditions it is the lightest solid element on the periodic table. Like all alkali metals, lithium is highly reactive and flammable and is stored in mineral oil. Lithium is widely found in the Earth's crust, but it does not occur as a specific mineral, that is, with a chemical composition and defined crystal structure, allowing its extraction in isolation in mineral deposits. In Brazil, it is always a component that forms the crystal structure of lithiniferous pegmatite minerals, such as spodumene (the only economically exploitable for lithium extraction), petalite, amblygonite, and elbaite, related to endogenous processes. In the exogenous environment, it occurs as a constituent of salt flats in Andean countries such as Argentina, Chile, and Bolivia. Its geological exploration is related to specific mining processes, with concentration by electrolysis. Lithium has many applications, from lubricating grease, alloy additions, in particular for Aluminum and Magnesium alloys, to glazes for ceramics, and finally Lithium batteries. In the field of psychiatry, lithium has established itself as an essential drug for the treatment of bipolar disorder, acting as a mood stabilizer by modulating neurotransmitters and neuronal processes. Thus, the present study seeks not only to highlight the geological processes involved in lithium extraction, but also to discuss the therapeutic contributions and clinical challenges associated with its use.

A theoretical and experimental search has been conducted for a model to explain the therapeutic effect of the "Philippine healer" - ultrafast healing of medical wounds. We came to the conclusion that the AIM+ - model is more suitable than the others. Previously [1-3] were presented: FK, DFK, AIM, AIM+ models.

The FK model is an elastic-periodic chain of atoms (CH1) in a periodic potential, which is described by commensurate and incommensurate phases.

In the DFK model, the periodic potential of the FK model is replaced by a second elastically periodic chain of atoms (CH2).

In the AIM model, the cosmological applications of the FK + DFK models are considered, through the creation of a time chain (CH1 + CH2), a type of open system.

The rubaiyat of Omar Khayyam voiced the cosmological idea of the AIM model: 

          “Oh, woe! Nothingness is embodied in our flesh,

           Nothingness is surrounded by a border of celestial spheres.

           We tremble in horror from birth to death:

           We are ripples on Time, but it is nothing.”

In the AIM+ model, CH1 atoms returning to the jerk point form a cloud of gas, which condenses on the energy excitations of the time chain (CH1+ CH2), forming associated states with them.

Let us call the emerging states “living cells” (LC). LCs can be two-dimensional, three-dimensional, etc. It is possible that the first three-dimensional LC was formed at the stage of inflationary growth of the Universe long before the point of the “Big Bang”; let’s call it “inflaton”. 

AIM+   model considers the phase of inflationary growth of the Universe as the initial stage of the development of a microbial colony.

It is known that communities of biological cells are open biological systems, which at the initial stages develop according to an exponential law (I-phase). But then they plateau very quickly. We believe that the I-phase can be extended by creating a coherent state for the LC (CR mode), when the entire community develops coherently.

In experiments [4, 5] the problem of creating one of the possible CR modes in microbiological systems was solved: - stimulating the growth of a colony of a microbiological culture of e.coli with a physical device with spatial coherence, by resonantly matching the size of a biological cell with the coherence period of the device. As a result: - we observed CR stimulated by an external field - modes with single and multiple subcultures of the microbiological culture. 

Many specialties in medicine and surgery are interested in the progress of the biomedical applications of the laser. Lasers are now becoming the treatment of choice by both clinicians and patients, and in some cases, the standard of care. The aim of this clinical study was to apply and assess the usefulness of diode laser 980nm in orofacial region. This clinical study was carried out at our private clinic using diode laser in many orofacial clinical applications. A total of 35 patients including 20 (≈57%) male and 10 (≈42%) female with age range from (3 to 58) years old. Overall satisfaction was observed in all clinical applications and proved to be of
beneficial effect for daily practice and considered practical, effective, easy to used, offers a safe, acceptable, and impressive alternative for conventional surgical techniques. Diode laser can be used in oral and facial soft tissue surgery because of easy application, better coagulation, no need for suturing, less swelling and pain, as well as for its capability for treatment of physiologic gingival pigmentation