Nowadays, sustainability and good use of resources and waste are necessary. So, this work seeks to synthesize a ceramic material from natural waste, as well as its characterization and biological evaluation after all the steps that anticipate in vivo application. In this way, brushite, which is a dihydrate dicalcium phosphate mineral that is a calcium phosphate present in the natural mineralization of tissues, can be obtained synthetically from chicken eggshells. It is used as a biomaterial for different applications such as medical treatment, especially orthopedic treatment and bone repair, agrobiological inorganic fertilizers. Brushite has the property of adsorbing ions and changing its active sites with calcium, such as Zn and Ag ions, which can enhance the biocompatible and bactericidal potential of the biomaterial, respectively. In this work, we started with the synthesis of bruxite nanopowders (previously performed) that was characterization by microscopy and physical-chemistry analysis (MEV-topography, MET-nanoscale, FTIR-chemistry-group, XRD Rietveld- material identity). The cytotoxicity was then tested by in vitro microbiological analysis in a nutrient medium using 3 species of bacteria was made ISO-10993-5- ceramic tests. The results shows that was possible to obtain bruxite through the results of chemical-physical characterization and the initial results in vitro indicate that it is a biocompatible nanoceramic. 

Thanks to Faperj 203.409/2023 - SEl-260003/016585/2023 for supporting the research, to CAPES, CNPQ and to the student Ronald Palandi Cardoso for helping with the cultivation of microorganisms and to Prof. Yutao Xing for helping with the MET analysis.