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SIPS 2024 takes place from October 20 - 24, 2024 at the Out of the Blue Resort in Crete, Greece

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More than 500 abstracts submitted from over 50 countries


Featuring many Nobel Laureates and other Distinguished Guests

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Oral Presentations


SESSION:
PharmaceuticalTuePM3-R4
Leuenberger International Symposium on Pharmaceutical Sciences and Industrial Applications for Sustainable Development
Tue. 22 Oct. 2024 / Room: Minos
Session Chairs: Hassan Tarabishi; Martin Bultmann; Student Monitors: TBA

16:45: [PharmaceuticalTuePM311] OS
SUSTAINABILITY IN BIG PHARMA – CAN SUPERCOMPUTING DO THE MAGIC?
Martin Bultmann1
1University of Heidelberg, Heidelberg, Germany
Paper ID: 101 [Abstract]

Though all industries can harvest low-hanging fruit in terms of sustainability (environmental, economic, social) in various aspects like waste-reduction, material/water/energy-consumption etc., pharma-specific SWOT analysis reveal internal and external obstacles for significant improvement: e.g. regulatory aspects, data handling, implementation of innovation.

Conservative and risk-avoiding internal/external regulatory bodies with different views and foci result in a downward spiral narrowing down the operational window, fostering only applying legacy approaches and create a hindering environment for implementing innovative technologies.

On the other hand, regulatory bodies are right asking for thorough understanding of products and processes (e.g. ICH Q8-10) which comprises the ability to rationally explain formulation and process.

Data, information, knowledge play a major role in creating that knowledge and wisdom around products, the human body and our industry in the widest sense. With vast amount of (unstructured) data available, supercomputing power, NN, AI, KBS are necessary prerequisites for harvesting knowledge. Plus, educating next generation scientists in best practices of (DOE-)data-evaluation, modelling, simulation becomes even more important to achieve next big steps in sustainability.

References:
[1] Deutsches Wörterbuch von Jacob Grimm und Wilhelm Grimm Band 13, Hirzel, Leipzig 1869, Spalte 69., digitalised version in Wörterbuchnetz des Trier Center for Digital Humanities, Version 01/23, , last visited 17.Apr.2024. https://woerterbuchnetz.de/?sigle=DWB&lemid=N00521
[2] Wikipedia „Nachhaltigkeit“ https://de.wikipedia.org/wiki/Nachhaltigkeit last visited 17.Apr.2024
[3] Wikipedia „Sustainability“ https://en.wikipedia.org/wiki/Sustainability last visited 17.Apr.2024
[4] Wikipedia „Eco-ecomomic decoupling“ https://en.wikipedia.org/wiki/Eco-economic_decoupling last visited 17.Apr.2024
[5] Purvis, B., Mao, Y. & Robinson, D. Three pillars of sustainability: in search of conceptual origins. Sustain Sci 14, 681–695 (2019). https://doi.org/10.1007/s11625-018-0627-5 - https://link.springer.com/article/10.1007/s11625-018-0627-5 CC BY-SA 4.0 File:Visualization of pillars of sustainability.webp, last visited 18.Apr.2024
[6] H. Stricker, Arzneiformen-Entwicklung: Feste Zubereitungen, Springer Berlin Heidelberg, 2012, ISBN 10: 364262393X, ISBN 13: 9783642623936
[7] H. Leuenberger, The Organic Supercomputer, able to Replicate as Virtual Patient, Proceedings 2023 SIPS Summit, Hyatt Playa Bonita, Panama City, Vol.11, sips23_65_63FS, Intern. Symp. on Technological Innovations in Medicine, edited by F. Kongoli, F. Murad, T. Yoshikawa, J.R. Ribas, D. Joseph, N. Tran, S. Hirano FLOGEN 2023.
[8] D. Campy, T. Eaves, EM. Grudzinski, HEC. Worthington, Scale up Considerations in fluidized bed granulation: air flow rates and air pressure distribution, 1974, J Pharm Pharmacol 26: 76P
[9] SK El-Arini, Wirbelschichtgranulation – Verfahrensoptimierung mittels Factorial Design, 1981, Pharm Ind 43: 674
[10] H. Leuenberger, G. Imanidis, Monitoring mass transfer process to control moist agglomeration, 1986, Pharm Technology 3:56
[11] G. Imanidis, Untersuchungen über die Agglomerierkinetik und die elektrische Leistungsaufnahme beim Granulierprozess im Schnellmischer, 1986, Dissertation, Universität Basel
[12] P. Bauer, V. Schreiber, FX Wohlzogen, Sequentielle statistische Verfahren, Fischer Stuttgart, New York, 1986, ISBN 3437203436
[13] United Nations Department of Economic and Social Affairs - Sustainability Development Goals https://sdgs.un.org/goals, last visited 22.Apr.2024
[14] D. Fiedler, C. Alva, J. Pinto, M. Spoerk, Martin, R. Jeitler, E. Roblegg, In-Vial Printing and Drying of Biologics as a Personalizable Approach, 2022, International journal of pharmaceutics. 623, 121909. 10.1016/j.ijpharm.2022.121909
[15] Corporate Sustainability Reporting Directive (CSRD), Bundesministerium für Arbeit und Soziales https://www.csr-in-deutschland.de/DE/CSR-Allgemein/CSR-Politik/CSR-in-der-EU/Corporate-Sustainability-Reporting-Directive/corporate-sustainability-reporting-directive-art.html, last visited 22.May 2024


17:25 POSTERS/EXHIBITION - Ballroom Foyer