Exposure to mutant and neglected disease resistant pathogen strains is high and presents a significant threat to public health, peace and economic mobility. The microbe outruns the R&D time-line for a new generation of drug. The microbe has changed its genome to outwit the therapy. Biological warfare poses a significant threat to a human population, operations of security personnel and emergency response specialists. Antibiotics and vaccine resistance renders the efficacy and potency of the current crop of antibiotics and treatments useless and expensive. 

Such challenges need to be significantly remedied with new solutions. A moving target pathogen can be eliminated via electrodynamic treatment of an infection in a human being. A move to do away with antibiotics is in sight. Electrodynamics can eliminate the microbe independent of its mutant strategies. The electrodynamic option for fast remedy is based on deeper insights on the definitions of terms thought of as understood in Physics. This paper will define the paradigm shift in understanding of everyday terms such as temperature, Ohm’s Law, electric charge, mass, frequency and wavelength.

The electrodynamic therapy to rid pathogens is a direct result of interdisciplinary research work in physics, chemistry, pharmacy and medicine. The rationale of this original research is in the realm of empirical biophysics.

The goals are specific, and the foundation work has been completed.

The results of this work will have worldwide impact since the diseases treated by this new regimen will help millions by destroying pathogens often identified at autopsy.

Inflammatory state and immunity are the two patient conditions that need to be addressed when infectious disease hits a population or when co-infection exists in chronic disease conditions. The Magellan Therapeutic Inc. platform addresses these two patient conditions. The method employs replenishing diminished levels of a key component of the lectin pathway by cell and gene therapy. The lectin pathway is responsible for immunity as well as inflammation. Every person on Earth has probably taken a small molecule or an injection of a steroid for inflammation or antibiotics to treat infection. The waste generated from the entire cycle from disposable plastics, gowns, masks, to biowaste from liquid biopsy, patient sputum, fecal and urine is a neglected aspect of disease burden. Moreover, the cost of generating potable water from contaminants ranging from drug excretion in sewage to disturbance in soil and water pH to drug resistant pathogen mutants is largely overlooked. A discussion on nipping these issues in the bud from bench to patient is presented. The dots are connected via simple diagrams for a snapshot of the bigger picture. Solutions to the crisis are provided for debate and implementation irrespective of political viewpoints. The goal post does not move. An alternative model in new trade free parks is proposed with sustained nondilutive funding. The goal is human flourishing.