ORALS

SESSION: ElectrochemistryMonPM2-R2	Amatore International Symposium on Electrochemistry for Sustainable Development
Mon Nov, 5 2018 / Room: Copacabana B (150/1st)
Session Chairs: Huangxian Ju; Session Monitor: TBA

15:55: [ElectrochemistryMonPM209] Invited
Photoelectrochemical Bioanalysis
Hong-yuan Chen¹ ; Wei-wei Zhao¹ ; Jing-juan Xu¹ ; ¹Nanjing University, Nanjing, China;
Paper Id: 69 [Abstract]

Photoelectrochemical (PEC) bioanalysis is a newly established analytical approach based on the photo- to-electrical properties of photoactive materials. It possesses many intrinsic advantages such as remarkable sensitivity, simple instrument, and inherent miniaturization. From the combination of photoelectrochemistry and bioanalysis, PEC bioanalysis has advantageously inherited the high sensitivity and specificity. Its general sensing mechanism is that, upon illumination, the photoactive materials could convert the specific biorecognition events into electrical signals, thereby realizing the quantification of various analytes. In past years, the rapid development of PEC bioanalysis has attracted considerable interest, and significant progress has been achieved in its advancement and application. This talk introduces the basic principles, classification, characteristics, as well as the recent progress of PEC bioanalysis in our group.

References:
[1] W. W. Zhao, J. J. Xu, H. Y. Chen, Anal. Chem. 90 (2018) 615-627.
[2] G. Wang, F. Yuan, T. Gu, Y. Dong, Q. Wang, W. W. Zhao, Anal. Chem. 90 (2018) 1942-1947.
[3] N. Zhang, Y. Ruan, L. Zhang, W. W. Zhao, J. J. Xu, H. Y. Chen, Anal. Chem. 90 (2018) 2341-2347.[4] L. Mei, X. Jiang, X. Yu, W. W. Zhao, J. J. Xu, H. Y. Chen, Anal. Chem. 90 (2018) 2749-2755.
[5] Q. Wang, Y. Ruan, W. W. Zhao, P. Lin, J. J. Xu, H. Y. Chen, Anal. Chem. 90 (2018) 3759-3765.

SESSION: ElectrochemistryTuePM1-R2	Amatore International Symposium on Electrochemistry for Sustainable Development
Tue Nov, 6 2018 / Room: Copacabana B (150/1st)
Session Chairs: Guobao Xu; Session Monitor: TBA

14:00: [ElectrochemistryTuePM105]
ECl Color Devices Based on Bipolar Electrode
Jing-juan Xu¹ ; Hong-yuan Chen¹ ; ¹Nanjing University, Nanjing, China;
Paper Id: 73 [Abstract]

ECL is a powerful tool for the study of electron transfer pathways and development of luminescent devices. Ru(II) and Ir(III) luminophores are the most commonly used concomitant electrochemiluminophores, owing to their high ECL efficiencies with TPrA as the co-reactant. Although the selective excitation of electrochemiluminophores was highly expected to open new avenues for multianalyte detection, over the years its application in this area was still limited. The major drawback is the weak solubility of Ir complexes in water, which limits the biological application of multi-color ECL. We adopted closed bipolar electrode (BPE), which solved the challenge by separating organic ECL emitters from the analyte. Selective excitation of the electrochemiluminophores (Ru(II) and Ir(III) luminophores) could be achieved by tuning the interfacial potential at the poles of BPE. Along with the increasing potential, the ECL intensities of the two emitters varied, and the emission color changed, which enabled us to detect biomarkers on a BPE array with different strategies. With a single DC power supply, prostate-specific antigen (PSA), circulating microRNA-141 (mRNA-141) and small molecular marker, sarcosine were simultaneously detected by the array.

References:
[1] Wang YZ, Ji SY, Xu HY, Zhao W, Xu JJ, Chen HY. Anal. Chem. 10.1021/acs.analchem.8b00014.
[2] Wang YZ, Xu CH, Zhao W, Guan QY, Chen HY, Xu JJ. Anal. Chem. 2017, 89 (15), 8050