Mr. Yoshiaki Harakawa

Abstract:

Acne vulgaris is one of the most common skin diseases with varying etiologies. Acne vulgaris is most often seen on the face and back, and especially acne on the face is associated with a change in appearance, which may lead to psychogenic stress. Treatment includes cosmetic treatments such as chemical peels and phototherapy, but generally they are treated with topical medications, vitamins, or antibiotics for a certain period of time. Acne, including rough skin, is caused by oxidative stress due to fatigue, irregular lifestyle, and ultraviolet rays, which leads to the deterioration of the skin barrier function. SOD activity and malondialdehyde (MDA) concentrations in tissue and blood levels depend on the severity of the acne. Especially in severe acne, low SOD activity and high MDA levels have been reported, clearly indicating that oxidative stress is involved in acne vulgaris. Twendee X, an antioxidant supplement consisting of eight active ingredients of vitamins, amino acids, and CoQ10, has passed drug-level safety testing and is safe for use in children and adults. Since Twendee X significantly reduces blood oxidative stress in healthy individuals, it is feasible to provide oxidative stress care in acne vulgaris. In addition, each of the ingredients in Twendee X may have the potential to reduce the recurrence and aggravation of acne. We will report on the potential of Twendee X as an antioxidant treatment for acne vulgaris, using the results of a questionnaire we have conducted to date.