2024 - Sustainable Industrial Processing Summit
SIPS2024 Volume 1. Abe Intl. Symp. / Oxidative Stress of Human Beings
| Editors: | F. Kongoli, H. Inufusa, T. Yoshikawa, C-A. Amatore, H-Y. Chen, W-H. Huang |
| Publisher: | Flogen Star OUTREACH |
| Publication Year: | 2024 |
| Pages: | ## pages |
| ISBN: | 978-1-998384-04-4 (CD) |
| ISSN: | 2291-1227 (Metals and Materials Processing in a Clean Environment Series) |
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A BLENDED VITAMIN SUPPLEMENT IMPROVES COGNITIVE FUNCTION IN AGED MICE
Koji Fukui1; Fuhua Yang2; Yugo Kato3; Ayuta Kishimoto1; Yoshiaki Harakawa2; Toshikazu Yoshikawa4; Haruhiko Inufusa2;1SHIBAURA INSTITUTE OF TECHNOLOGY, Saitama, Japan; 2GIFU UNIVERSITY, Gifu, Japan; 3TOTTORI UNIVERSITY, Yonago, Japan; 4LOUIS PASTEUR CENTER, Kyoto, Japan;
Type of Paper: Keynote
Id Paper: 142
Topic: 54
Abstract:
Many types of antioxidant supplements are available in the private market in Japan. However, it is difficult to know which type and how much to take, as it is possible to take too many of some vitamins. Since it is difficult for general consumers to make a choice, it is important to provide information based on scientific evidence. This study investigated the effects of continuous administration of a blended supplement, Twendee X (TwX) to aging mice. When 18-month-old C57BL/6 mice were given TwX for 1 month, behavioral tests showed that special cognition and short-term memory significantly improved compared to the age-matched controls. There were no significant differences in secreted neurotrophic factors, such as nerve growth factor and brain-derived neurotrophic factor in the brain. In treadmill durability tests before and after administration, the rate of increase in running distance after administration was significantly higher than that of the untreated group. These results suggest continuous intake of TwX may improve cognition and suppress age-related muscle decline. There is no problem with overdosing, so we think it's a good idea to take the blended supplement continuously.