2024 - Sustainable Industrial Processing Summit
SIPS 2024 Volume 1. Abe Intl. Symp. / Oxidative Stress and Technological Innovations in Medicine
| Editors: | F. Kongoli, H. Inufusa, T. Yoshikawa, C.A. Amatore, H-Y. Chen, W-H. Huang |
| Publisher: | Flogen Star OUTREACH |
| Publication Year: | 2024 |
| Pages: | 218 pages |
| ISBN: | 978-1-998384-04-4 (CD) |
| ISSN: | 2291-1227 (Metals and Materials Processing in a Clean Environment Series) |
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CELLULAR AND ANTIBACTERIAL PROPERTIES OF TiN-Cu COMPOSITE COATINGS INDUCED BY Mg+ IMPLANTATION
Dejun Li1;1TIANJIN NORMAL UNIVERSITY, Tianjin, China;
Type of Paper: Regular
Id Paper: 11
Topic: 65
Abstract:
Titanium alloy (Ti-6Al-4V) has been widely used in medical field due to its good biocompatibility and machinability. However, Ti-6Al-4V lacks antibacterial ability, which can be easy to lead the surgical infection by bacteria. At the same time, the release of the toxic ions such as Al or V in Ti-6Al-4V to the human body under the physiological environment is also easy to cause harm to the human body. Therefore, in order to solve the above problems, this study first used magnetron sputtering technique to prepare TiN-Cu composite coatings on the surface of Ti-6Al-4V, which is expected to take advantage of Cu's antibacterial properties to achieve long-term antibacterial effects while preventing the release of toxic ions. Second, in order to enhance cell adhesion of the TiN-Cu composite coatings, plasma immersion ion implantation (PIII) was used to implant Mg ions into the surface of the composite coatings respectively. A series of measurements (such as XRD, XPS, SEM, etc.) were used to analyze the structure, composition and mechanical properties of TiN-Cu composite coatings before and after implantation with different ions. L929 cells and Mc3t3-e1 cells were used to analyze the cell proliferation and adhesion on the sample surfaces. The survival of Escherichia coli by using the coating plate method. The results showed that the surface of Mg+ implanted TiN-Cu composite film had the best antibacterial property and cell proliferation ability with the highest protein adsorption ability. Cu trapped electrons on the bacteria's surface and destroyed their membranes. In addition, the bonding of Cu and respiratory enzymes in the bacteria also caused bacterial dysfunction. The implanted Mg+ on the surface stimulated protein adsorption, the cell adhesion and proliferation.