Peter Rowlands's development of fundamental physics using the nilpotent concept opens up deeper questions about homological applications of the same topological relationships in other domains. I will argue that the very idea of a homological relationship between one set of phenomena conceived in terms of a Clifford algebra, and another set of phenomena, may itself be attributable to the fact that the perception of homology derives from equivalences of "nothing" at different levels. To demonstrate this, examples can be drawn from fields as diverse as AI and music.