It has been proposed that life is a Singularity (1). The primary means of sustaining that state biologically is Symbiogenesis, the assimilation of factors in the environment that pose existential threats. But why not just destroy them? Answer: Because then there would be no history to reference in order to evolve effectively. Moreover, given that, Symbiogenesis must have evolved from a Singularity as its reference point, generating a ‘holism’. This hypothetically answers the question as to where mathematics emerged from as follows. Tegmark (“Our Mathematical Universe”) stipulates that math is inherent to the Cosmos; since Symbiogenesis  passively assimilates the math inherent to the Cosmos, incorporating it into physiology as the basis of consciousness, there is a seamless integration of math both physiologically and consciously. For example, Rowlands’ Rewrite Math (“Foundations of Physical Law”) mirrors the mechanism of Epigenetic Inheritance, Rowlands’ zero ‘attractor’ behaving like the cell does, a new datum assessed by the existing data set behaving in the same way as the egg and sperm of the parent, facilitating adaptation to change. Lou Kauffman’s ‘Knot Math’ similarly resembles embryogenesis, the twisting of the circle generating knots, the twisting of the embryo generating the stages of its development. Proof of a true ‘knot’ is the ability to unknot it to re-form the circle; homologously, the cell must undergo meiosis to form the egg or sperm in order to then reproduce. And Soft Logic Math as the family of real numbers and ‘zeroes’ reflects how physiology has evolved as a two-tiered system, the real numbers being the horizontal accumulation of data, the family of zeroes as the vertical generation of physiologic traits ontogenetically and phylogenetically. This  intimate relationship between the Singularity, Symbiogenesis and evolution can also be seen as a Fibonacci sequence, the Singularity (1) + Symbiogenesis (2) = Evolution (3), or 1 + 2 = 3, out of which emerges empathy as a product. These fundamental insights provide for sustainability of life based on the ubiquity of the Fibonacci sequence.