2023-Sustainable Industrial Processing Summit
SIPS2023 Volume 11. Intl. Symp on Technological Innovations in Medicine
| Editors: | F. Kongoli, F. Murad, T. Yoshikawa, J.R. Ribas, D. Joseph, N. Tran, S. Hirano |
| Publisher: | Flogen Star OUTREACH |
| Publication Year: | 2023 |
| Pages: | 126 pages |
| ISBN: | 978-1-989820-92-6 (CD) |
| ISSN: | 2291-1227 (Metals and Materials Processing in a Clean Environment Series) |
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SINGLE MOLECULE STUDIES OF ENZYMES AND INTERCONVERSION OF MECHANICAL AND CHEMICAL ENERGY IN A BIOLOGICAL MACHINE, F1ATPase, THEORY AND EXPERIMENT
Rudy A. Marcus1;1CALTECH, California, United States;
Type of Paper: General Plenary
Id Paper: 501
Topic: 46
Abstract:
There have now been many experimental studies of a biological machine, such as F1ATPase, at the single molecule level. They provide informatonn on how nature can interconvert chemical and mechanical energy. These experiments include controlled rotation, free rotation, and stalling experiments. We desccibe a theoretical interpretation of these results using a theory that is an extension one introduced for simple electron transfer and other transfer processes.We also use the theory as a basis to develop methods for analyzing the single-molecule imaging and manipulation trajectories. This work was performed in collaboration with Proofessors, Sandor Volkan-Kacso and Ricardo Matute.