Nanodispersed iron oxides obtained using the electroerosion dispersion (EED) technology [1-3] were developed by M. Monastyrov, and used to produce dietary supplement Lisoferrin^TM and feed additive Nano-Fe+^TM. The supplement and additive were certified in Ukraine and Poland.The effects of composition of polyvalent nanodisperse iron oxide, quercetin and vitamin C - Lisoferrin^TM was studied on 60 women with metabolic syndrome (MS) who were divided equally into the main and control groups. Patients of the main group received dietary supplement Lizoferrin^TM, patients of the control group received a placebo. Anthropometric indicators, blood plasma glucose fasting and 2h after oral glucose tolerance test (OGTT), fasting blood serum lipids, microvascular endothelium function were determined before and 1 month after use of Lizoferrin^TM or placebo. The use of Lizoferrin^TM led to a decrease fasting plasma glucose and glucose level 2h after OGTT in patients with prediabetic disorders. Serum concentration of total cholesterol and low-density lipoproteins cholesterol were decreased in individuals with atherogenic dyslipidemia. Along with this, there was an improvement in the functional state of the endothelium of microvessels, which is evidenced by an increase in the maximum volume velocity of skin blood flow as tested with reactive hyperemia. The beneficial effects of polyvalent nanodisperse iron oxide, quercetin and vitamin C on cardiovascular risk factors were demonstrated by the authors for the first time in patients with metabolic syndrome [4] .

The efficiency of nanodispersed iron oxide powder solved in glycerin - nano-Fe+^TM was studied during agricultural animal growing. The dosage of nano-Fe+^TM feed additive was carried out at the rate of 0.1 mg of powder per 1 kg of live weight of animals per day. According to the results of research, the effectiveness of the nano-Fe+^TM during the cultivation of various species and technological groups of agricultural animals (suckling piglets, young pigs in the growing period and young sheep in the growing period) has been established. The use of the nano-Fe+^TM contributes to an increase in productivity - increases in the live weight of piglets by 11.4%, young pigs by 7.7%, young sheep by 7.3%. The effectiveness of the nano-Fe+^TM is confirmed by the data obtained during the research on the average daily increase in the live weight of animals, the difference between young pigs and sheep during the growing period of the experimental and control groups according to this indicator was statistically significant in favor of the animals of the experimental groups (Р < 0.05). For example, the difference in average daily live weight gains between young pigs of the experimental (403 ± 36 g) and control (343 ± 39 g) groups is 60 g (17.5%).

The preservation of the animal population of the experimental groups is at the same level as the control group and is 100%. Nano-dispersed iron oxide powder (nano-Fe+^TM) is characterized by its effectiveness during the cultivation of young farm animals and was recommended for use on livestock farms in Ukraine by L. Pogorilyy UkrNDIPVT.