Christian Andre AmatoreCNRS & PSL, French Academy of SciencesUnderstanding Oxidative Stress In Brain With Ultramicroelectrodes: Implications For A Possible Mechanism Of Alzheimer Disease Yoshikawa International Symposium (2nd Intl. Symp. on Oxidative Stress for Sustainable Development of Human Beings) Back to Plenary Lectures » | |
Abstract:Oxidative stress is an essential metabolic outcome in aerobic organisms due to the activity of mitochondria in providing the basic energy of cells or during the operation of several enzymatic pools. It also serves to regulate the size and shape of organs or restructure them during foetal development by apoptosis. Oxidative stress is also indispensable to the immune system by allowing macrophages to eliminate virus, bacteria and impaired or dead cells through phagocytosis [1]. In fact, no aerobic organism could live without oxidative stress, a fact that explains why evolution maintained such unsafe mechanisms in aerobic organisms. Though, they are associated to highly negative issues. |