Research on research: bird's eye views on science and its reproducibility John Ioannidis1; 1STANFORD UNIVERSITY, United States, United States; PAPER: 515/Medicine/Plenary (Oral) SCHEDULED: 12:45/Tue. 29 Nov. 2022/Ballroom B ABSTRACT: Multiple lines of evidence suggest that a substantial segment of published research yields results that are not reproducible. In the last decade, we have had the ability to examine large segments of the scientific corpus, using methods that can provide bird’s eye views of the status and evolution of scientific disciplines in terms of reproducibility, transparency, and bias indicators. The lecture will assess the scope of this evidence and will discuss solutions that have been proposed to enhance the credibility of research efforts. Many of these solutions are already effective and have improved the performance of multiple scientific fields while others are more speculative and they require careful testing before their adoption. |