| Antioxidant treatment for Long- COVID and mRNA vaccine side effects Haruhiko Inufusa1; Fuhua Yang2; Naomi Okada3; Toshikazu Yoshikawa4; 1TIMA, Gifu, Japan; 2DIVISION OF ANTI-OXIDANT RESEARCH, GIFU UNIVERSITY, Gifu, Japan; 3GIFU UNIVERSITY, Gifu, Japan; 4LOUIS PASTEUR CENTER, Kyoto, Japan; PAPER: 425/Oxidative/Plenary (Oral) SCHEDULED: 14:00/Tue. 29 Nov. 2022/Ballroom B ABSTRACT: COVID-19 infection produces large amounts of Reactive Oxygen Species (ROS) in the human body, and the attack on the immune system by ROS causes a cytokine storm. Therefore, COVID19 infection generally does not cause severe disease in children with low ROS levels, but often causes severe disease and death in the elderly or those with underlying disease already ROS levels are high. The major problem with after COVID-19 pandemic is not only Long-COVID, but also the large number of patients who suffer from the tremendous side effects caused by mRNA vaccines. Pfizer and other genetic vaccines produce spike proteins and antibodies against them. Not only the spike protein itself causes ROS, but also pseudouridine and Lipid Nanoparticles (LNP) contained in the vaccine induce inflammation and increase ROS. In other words, both diseases are oxidative stress diseases. Twendee X (TwX) is a very strong antioxidant composition and reduces inflammation which L-glutamine, ascorbic acid (VC), L-cystine, coenzyme Q10, succinic acid, fumaric acid, vitamin B2, and niacin was used for patients. Patients took 3 tablets of TwX once a day for 4 weeks and answered a web-based questionnaire about their symptoms before and after taking TwX. A score of 0 on the questionnaire indicated no symptoms, while a score of 5 indicated severe symptoms. A total of 149 patients with mRNA vaccine sequelae completed the monitoring questionnaire completely. The monitored symptoms were Fatigue, Breathing difficulty, Chest pain, Smell or taste disorder, Headache, Brain fog, Joint pain, and Dizziness. All monitored symptoms showed significant post-medication score reductions and symptom improvement. Especially in patients with moderate to severe disease with a score of 3 or higher, the mean score dropped to less than half of the pre-medication level for all items. TwX were thought to be effective in relieving symptoms in these patients, many of whom suffer from mRNA vaccine sequelae worldwide. References: 1). Novel compositions and uses thereof WO 2008071790 A3<br />2). Antioxidant composition and its use in diabetes EP 1932542 A1<br />3). Pretreatment Twendee X® reduced acute ischemic brain damage. Kusaki M, Inufusa H, Abe K, JSCVD 2017; 26: 1191-1196<br />4). Clinical and Pathological Benefit of Twendee X in Alzheimer's Disease Transgenic Mice with Chronic Cerebral Hypoperfusion. Liu Xia, Yamashita T, Abe K, et al. J Stroke Cerebrovasc Dis. 2019 Jul;28(7):1993-2002.<br />5). Antioxidant composition Twendee X may improve long COVID symptoms. You F, Tanaka S, Inufusa H, et al. Brain Supplement. 2022; 4: 7-12.<br />6). Effects of Antioxidant composition Twendee X on side effects of SARS -COV-2 mRNA vaccine. You F, Tanaka S, Inufusa H, et al. Brain Supplement. 2022; 4: 1-6. |
