2018 - Sustainable Industrial Processing Summit & Exhibition
4-7 November 2018, Rio Othon Palace, Rio De Janeiro, Brazil
| ECl Color Devices Based on Bipolar Electrode Jing-juan Xu1; Hong-yuan Chen1; 1NANJING UNIVERSITY, Nanjing, China; PAPER: 73/Electrochemistry/Regular (Oral) SCHEDULED: 14:00/Tue./Copacabana B (150/1st) ABSTRACT: ECL is a powerful tool for the study of electron transfer pathways and development of luminescent devices. Ru(II) and Ir(III) luminophores are the most commonly used concomitant electrochemiluminophores, owing to their high ECL efficiencies with TPrA as the co-reactant. Although the selective excitation of electrochemiluminophores was highly expected to open new avenues for multianalyte detection, over the years its application in this area was still limited. The major drawback is the weak solubility of Ir complexes in water, which limits the biological application of multi-color ECL. We adopted closed bipolar electrode (BPE), which solved the challenge by separating organic ECL emitters from the analyte. Selective excitation of the electrochemiluminophores (Ru(II) and Ir(III) luminophores) could be achieved by tuning the interfacial potential at the poles of BPE. Along with the increasing potential, the ECL intensities of the two emitters varied, and the emission color changed, which enabled us to detect biomarkers on a BPE array with different strategies. With a single DC power supply, prostate-specific antigen (PSA), circulating microRNA-141 (mRNA-141) and small molecular marker, sarcosine were simultaneously detected by the array. References: [1] Wang YZ, Ji SY, Xu HY, Zhao W, Xu JJ, Chen HY. Anal. Chem. 10.1021/acs.analchem.8b00014. [2] Wang YZ, Xu CH, Zhao W, Guan QY, Chen HY, Xu JJ. Anal. Chem. 2017, 89 (15), 8050 |
