Synthesis and Structural Characterization of Silver Nanoparticles (Ag NPs) for Joint Pain Formulation Application
Akbar
Ali1; Umer
Balil2; Nasir
Mehboob2; Mukhtar
Ahmad1; Ghazanfar
Abbas1; hammad
aziz3; Muhammad Junaid
Amjad4;
1COMSATS LAHORE, lahroe, Pakistan; 2RIPHAH UNIVERSITY ISLAMABAD, Islamabad, Pakistan; 3COMSATS LAHORE., Lahore, Pakistan; 4COMSATS LAHORE, Lahore, Pakistan;
Type of Paper: Regular
Id Paper: 333
Topic: 18Abstract:
Synthesis and structural characterization of acetaminophen loaded silver nano particles for joint pain Formulation applications were investigated. Silver nanoparticles (Ag NPs) were synthesized by chemical reduction method. The above mentioned synthesized materials were characterized by applying scanning electron microscope (SEM) and X-ray diffraction, UV-VI Spectroscopy for confirmation of morphological analysis, compositional purity, crystalline property, emission and free drug which is present in supernatant characteristics as well. In order to Open ended tube method is used to determine the drug release efficiency of acetaminophen loaded silver nano particles. A suspension of silver nano particle is prepared by mixing AGNPS in water. Then 10 mg, 20mg, 30mg, 40mg, 50mg, and 60mg of acetaminophen is accurately measured and mixed in 100 ml of AGNPS suspension. The mixture of acetaminophen and silver nano particle is incubated for 24 hours under the string. The resulting mixture is centrifuged at 10000 rpm for 60 minutes. Pallets thus obtained are redispersed in water for further characterizations. Free drug present in supernatant is measured by UV-VI Sspetroscopy.
Keywords:
Nanoparticles;
References:
[1] D.R. Boverhof ,C. M.Bramante , J. H. Butala , S. F. Clancy,M. Lafranconi, J. West, S. C. Gordon. Regulatory Toxicology and Pharmacolog73,150(2015)
[2] J.Chin,Chem.Soc.56,703(2009).
[3] W.Shi,Z.Ma,Biosens.Bioelectron.26,1098(2010).
[4] X.L.Luo,J.J.Xu,Q.Zhang,G.J.Yang,H.Y.Chen,Biosens.Bioelectron.21, 190(2005).,
[5] A.Kaushiketal,Biosens.Bioelectron.24,676(2008).
[6] N. Ratcliffe, P. Azambuja, C. B. Mello . Evidence-Based Complementary and Alternative Medicine 2014, 21 (2014).
[7] G. R. Rudramurthy , M. K. Swamy , U. R. Sinniah ,A. Ghasemzadeh Molecules , 21, 836 (2016).
[8] X.Kang,Z.Mai,X.Zou,P.CaiJ.J.Mo,Nanosci.Nanotechnol.7,1618(2007)
[9] Y.G.Sun,Y.N.Xia,Science.298,2176(2002).
[10] M.X.Kan,X.J.Wanga,H.M.Zhan.Chin,Chem Lett.22,458(2011).
[11] C.Ren,Y.Song,Z.Li,G.Zhu.Anal.Bioanal.Chem.381,1179(2005).
[12] Z.P.Chen,etal.Biosens.Bioelectron.23,485(2007).
[13] X.Q.Liu,S.W.Tao,Y.S.Shen,Sens.ActuatorsB.Chem.40,161(1997).
[14] L.C.Hsu,Y.Y.Li,C.G.Lo,C.W.Huang,G.Chern,J.Phys.D:Appl.Phys41,185003(2008).
[15] L.X.Yang,Y.Liang,H.Ceng,L.Y.Kong,W.Jiang,Bull.Mater.Sci.31919(2008).
[16] A.Ali,M.FAlam,N.Abbas,Z.Wazir,M.Willander,M.Tufail,M.Atif.Optelectronics and Advanced Materials Rapid Communications.8,1242(2014).Full Text:
Click here to access the Full TextCite this article as:
Ali A, Balil U, Mehboob N, Ahmad M, Abbas G, aziz h, Amjad M. (2017).
Synthesis and Structural Characterization of Silver Nanoparticles (Ag NPs) for Joint Pain Formulation Application.
In Kongoli F, Braems I, Demange V, Dubois JM, Pech-Canul M, Patino CL, Fumio O
(Eds.), Sustainable Industrial Processing Summit
SIPS 2017 Volume 8: Surfaces and Interfaces(SISAM), Composite, Ceramic and Nanomaterials
(pp. 233-244).
Montreal, Canada: FLOGEN Star Outreach