2014-Sustainable Industrial Processing Summit
SIPS 2014 Volume 5: Composite, Ceramic, Quasi-crystals, Nanomaterials & Coatings
| Editors: | Kongoli F |
| Publisher: | Flogen Star OUTREACH |
| Publication Year: | 2014 |
| Pages: | 578 pages |
| ISBN: | 978-1-987820-07-2 |
| ISSN: | 2291-1227 (Metals and Materials Processing in a Clean Environment Series) |
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FABRICATION AND CHARACTERIZATION OF RADIATION MODIFIED BIORESORBABLE POLYMERIC COMPOSITE FILM
Kamol Dey1; Ruhul Khan2;1DEPARTMENT OF APPLIED & ENVIRONMENTAL CHEMISTRY, UNIVERSITY OF CHITTAGONG, Chittagong, Bangladesh; 2BANGLADESH ATOMIC ENERGY COMMISSION, Dhaka, Bangladesh;
Type of Paper: Regular
Id Paper: 365
Topic: 16
Abstract:
Bio-resorbable composite has gained tremendous interest in the field of biomaterials research. Ionizing radiation offers unique advantages for the modification of polymers for biomedical applications. In the present study, bioactive and biodegradable polymers chitosan and gelatin were used to prepare bio-absorbable composite film through solution casting process followed by UV irradiation with different dose strength. 2-hydroxyethyl methacrylate (HEMA) was used as a cross-linking monomer and phosphate glass (PG) as a reinforcement filler. The composite films were obtained by diluting gelatin (G), phosphate glass (PG) and HEMA with G: PG ratio of 88:12 wt%, G: HEMA ratio of 50:50 wt% and G: PG: HEMA ratio of 44:12:44 wt% in hot water. Incorporation of PG improved the mechanical properties of the composite films. Stereo microscope analysis revealed the porous nature of UV irradiated composite film. The chitosan film was prepared in 2% acetic acid solution and the prepared film was soaked into HEMA monomer containing methanol solvent and photo initiator for various time span to investigate the monomer concentration, soaking time and solvent effect on the performance of chitosan film. UV radiation was employed to induce cross-linking and photo-grafting. The evidence of cross-linking and grafting was provided by Fourier Transform Infrared Spectroscopy. The results regarding monomer and solvent concentration as well as UV dose intensity on the yield of cross-linking were presented in terms of polymer loading, mechanical performance, water absorbance and thermal stability. The prepared composite films can have a potential use in biomedical application both in drug delivery and tissue engineering.